Kahsai, A.W.; Cui, J.; Kaniskan, H.Ü.; Garner, P.P.; Fenteany, G. Analogs of tetrahydroisoquinoline natural products that inhibit cell migration and target galectin-3 outside of its carbohydrate-binding site. J. Biol. Chem. 2008, 283, 24534-24545. [Abstract] [HTML] [PDF]
Beshir, A.B.; Guchhait, S.K.; Gascón, J.A.; Fenteany, G. Synthesis and structure-activity relationships of metal-ligand complexes that potently inhibit cell migration. Bioorg. Med. Chem. Lett. 2008, 8, 498-504. [Abstract] [HTML] [PDF]
Mc Henry, K.T.; Montesano, R.; Zhu, S.; Beshir, A.B.; Tang, H.-H.; Yeung, K.; Fenteany, G. Raf kinase inhibitor protein positively regulates cell-substratum adhesion while negatively regulating cell-cell adhesion. J. Cell. Biochem. 2008, 103, 972-985. [Abstract] [HTML] [PDF]
Kahsai, A.W.; Zhu, S.; Wardrop, D.J.; Lane, W.S.; Fenteany, G. Quinocarmycin analog DX-52-1 inhibits cell migration and targets radixin, disrupting interactions of radixin with actin and CD44. Chem. Biol. 2006, 13, 973-983. [Abstract] [HTML] [PDF]
Stossel, T.P.; Fenteany, G.; Hartwig, J.H. Cell surface actin remodeling. J. Cell Sci. 2006, 119, 3261-3264. [Abstract] [HTML] [PDF]
Farooqui, R.; Zhu, S.; Fenteany, G. Glycogen synthase kinase-3 acts upstream of ADP-ribosylation factor 6 and Rac1 to regulate epithelial cell migration. Exp. Cell Res. 2006, 312, 1514-1525. [Abstract] [HTML] [PDF]
Zhu, S.; Mc Henry, K.T.; Lane, W.S.; Fenteany, G. A chemical inhibitor reveals the role of Raf kinase inhibitor protein in cell migration. Chem. Biol. 2005, 12, 981-991. [Abstract] [HTML] [PDF] (This work was highlighted in Chem. Biol. 12, 953-954.)
Farooqui, R.; Fenteany, G. Multiple rows of cells behind an epithelial wound edge extend cryptic lamellipodia to collectively drive cell-sheet movement. J. Cell Sci. 2005, 118, 51-63. [Abstract] [HTML] [PDF] (This work was highlighted in J. Cell Sci. 118, 103e.)
Altan, Z.M.; Fenteany, G. c-Jun N-terminal kinase regulates lamellipodial protrusion and cell sheet migration during epithelial wound closure by a gene expression-independent mechanism. Biochem. Biophys. Res. Commun. 2004, 322, 56-67. [Abstract] [HTML] [PDF]
Fenteany, G.; Glogauer, M. Cytoskeletal remodeling in leukocyte function. Curr. Opin. Hematol. 2004, 11, 15-24. [Abstract] [HTML] [PDF]
Ankala, S.V.; Fenteany, G. Aryl, alkyl bis-silyl ethers: rapid access to monoprotected aryl alkyl and biaryl ethers. Synlett 2003, 6, 825-828.[PDF]
Fenteany, G.; Zhu, S. Small-molecule inhibitors of actin dynamics and cell motility. Curr. Topics Med. Chem. 2003, 3, 593-616. [Abstract] [PDF]
Mc Henry, K.T.; Ankala, S.V.; Ghosh, A.K.; Fenteany, G. A non-antibacterial oxazolidinone derivative that inhibits epithelial cell sheet migration. ChemBioChem 2002, 11, 1105-1111. [Abstract] [HTML] [PDF] (This work was highlighted in Trends Biochem. Sci. 27, 605 and Drug Discovery Today 8, 6-7.)
Ankala, S.V.; Fenteany, G. Selective deprotection of either aryl or alkyl silyl ethers from aryl, alkyl bis-silyl ethers. Tetrahedron Lett. 2002, 43, 4729-4732. [Abstract] HTML] [PDF]
Fenteany, G.; Janmey, P.A.; Stossel, T.P. Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets. Curr. Biol. 2000, 10, 831-838. [Abstract] [HTML] [PDF]
Corey, E.J.; Li, W.Z.; Nagamitsu, T.; Fenteany, G. The structural requirements for inhibition of proteasome function by the lactacystin-derived β-lactone and synthetic analogs. Tetrahedron 1999, 55, 3305-3316. [Abstract] [PDF]
Fenteany, G.; Schreiber, S.L. Lactacystin, proteasome function, and cell fate. J. Biol. Chem. 1998, 273, 8545-8548. [HTML] [PDF]
Degnan, B.M.; Degnan, S.M.; Fenteany, G.; Morse, D.E. A Mox homeobox gene in the gastropod mollusc Haliotis rufescens is differentially expressed during larval morphogenesis and metamorphosis. FEBS Lett. 1997, 411, 119-122. [Abstract] [PDF]
Craiu, A.; Gaczynska, M.; Akopian, T.; Gramm, C.F.; Fenteany, G.; Goldberg, A.L.; Rock, K.L. Lactacystin and clasto-lactacystin β-lactone modify multiple proteasome β-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation. J. Biol. Chem. 1997, 272, 13437-13445. [Abstract] [HTML] [ PDF]
Fenteany, G.; Schreiber, S.L. Specific inhibition of the chymotrypsin-like activity of the proteasome induces a bipolar morphology in neuroblastoma cells. Chem. Biol. 1996, 3, 905-912. [Abstract] [PDF]
Fenteany, G.; Standaert, R.F.; Lane, W.S.; Choi, S.; Corey, E.J.; Schreiber, S.L. Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin. Science 1995, 268, 726-731. [Abstract] [HTML] [PDF]
Fenteany, G.; Standaert, R.F.; Reichard, G.A.; Corey, E.J.; Schreiber, S.L. A β-lactone related to lactacystin induces neurite outgrowth in a neuroblastoma cell line and inhibits cell cycle progression in an osteosarcoma cell line. Proc. Natl. Acad. Sci. USA 1994, 91, 3358-3362. [Abstract] [PDF]
Fenteany, G.; Morse, D.E. Specific inhibitors of protein synthesis do not block RNA synthesis or settlement of planktonic larvae in a marine gastropod mollusc (Haliotis rufescens). Biol. Bull. 1993, 184, 6-14. [Abstract] [PDF]